Banerjee Lab



Theory of Living Matter

We develop theory and computational models of living systems and processes

One of the grand challenges of the 21st century is to understand, control, and re-engineer a living system from its many component parts to reconstitute the unique functions, structures, and material properties that define life. Our lab takes on this challenge by building quantitative models rooted in physics that bring out the design rules sculpting biological form, function, and behaviour across different spatiotemporal scales and organisational levels. Our work is organised around three main themes:

Mechanics of subcellular organization: How does a cell build and organize its internal structures to control its mechanical behavior?
Single-cell biophysics: How do single cells coordinate their growth with replication cycle to control their size, shape and biophysical activities?
Collective behavior in multicellular systems: How do cells in a population communicate, coordinate and cooperate to successfully proliferate, transmit mechanical forces, and repair damages?

Latest Papers

Smiley face Size-regulated symmetry breaking in reaction-diffusion models of developmental transitions
Scoones JC, Banerjee DS, and Banerjee S, Cells 9, 1646 (2020)

Smiley face Cell-type specific mechanical response and myosin dynamics during retinal lens development in Drosophila
Blackie L et al, Mol Biol Cell 31, 1355 (2020)

Smiley face The Actin Cytoskeleton as an Active Adaptive Material
Banerjee S et al, Ann Rev Cond Mat Phys 11, 421 (2020)

Smiley face RhoA mediates epithelial cell shape changes via mechanosensitive endocytosis
Cavanaugh K et al, Dev Cell 52, 152 (2020)

Smiley face Mechanosensitive junction remodelling promotes robust epithelial morphogenesis
Staddon MF et al, Biophysical Journal 117, 1739 (2019)

Smiley face Surface-to-volume scaling and aspect ratio preservation in rod-shaped bacteria
Ojkic N et al, eLife 8, e47033 (2019)

Smiley face Tissue fluidity promotes epithelial wound healing
Tetley RJ et al, Nature Physics 15, 1995 (2019)



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Contact Information

Mailing Address:
Prof. Shiladitya Banerjee
Department of Physics
Carnegie Mellon University
5000 Forbes Ave
Pittsburgh, PA 15213
United States

Email: shiladtb AT andrew.cmu.edu
Phone: (+1) 412-268-9418
Office: Wean Hall 6301 [Map]